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Lei Zhang Selected Research

Fibrosis (Cirrhosis)

4/2024Renal protective effects and mechanisms of Astragalus membranaceus for diabetic kidney disease in animal models: An updated systematic review and meta-analysis.
4/2024A combined pre- and intra-operative nomogram in evaluation of degrees of liver cirrhosis predicts post-hepatectomy liver failure: a multicenter prospective study.
3/2024The disordered extracellular matrix landscape induced endometrial fibrosis of sheep: A multi-omics integrative analysis.
3/2024[Mechanism of ultrafiltration extract of Angelicae Sinensis Radix and Hedysari Radix regulates HIF-1α signaling pathway mediated by renal hypoxia to ameliorate renal fibrosis in DKD rats].
2/2024Single-Cell Transcriptome Analysis Identified Core Genes and Transcription Factors in Mesenchymal Cell Differentiation during Liver Cirrhosis.
1/2024Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor).
1/2024Renal-protective effects of Chinese medicinal herbs and compounds for diabetic kidney disease in animal models: protocol for systematic review and meta-analysis.
1/2024MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis.
1/2024DNA methylation of SMPD3-based diagnostic biomarkers of NASH and mild fibrosis.
12/2023Knockdown of TXNDC5 alleviates CCL4-induced hepatic fibrosis in mice by enhancing endoplasmic reticulum stress.
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Lei Zhang Research Topics

Disease

1378Neoplasms (Cancer)
12/2024 - 02/2002
306Inflammation (Inflammations)
04/2024 - 10/2004
267Infections
05/2024 - 11/2002
198Neoplasm Metastasis (Metastasis)
04/2024 - 08/2005
166Hepatocellular Carcinoma (Hepatoma)
04/2024 - 06/2002
157Breast Neoplasms (Breast Cancer)
04/2024 - 12/2004
130Carcinogenesis
02/2024 - 02/2002
117Fibrosis (Cirrhosis)
04/2024 - 05/2005
104Hypoxia (Hypoxemia)
04/2024 - 12/2004
98Wounds and Injuries (Trauma)
05/2024 - 04/2004
95Carcinoma (Carcinomatosis)
03/2024 - 07/2005
93Stroke (Strokes)
03/2024 - 06/2003
88Lung Neoplasms (Lung Cancer)
12/2024 - 05/2005
84Colorectal Neoplasms (Colorectal Cancer)
04/2024 - 11/2011
83Obesity
05/2024 - 01/2005
81Alzheimer Disease (Alzheimer's Disease)
05/2024 - 07/2009
80Cardiovascular Diseases (Cardiovascular Disease)
05/2024 - 06/2003
80Hemorrhage
04/2024 - 11/2005
79Body Weight (Weight, Body)
05/2024 - 10/2005
78Ischemic Stroke
04/2024 - 07/2009
77Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2024 - 11/2008
77Stomach Neoplasms (Stomach Cancer)
01/2024 - 11/2010
74Type 2 Diabetes Mellitus (MODY)
03/2024 - 03/2010
73Pain (Aches)
02/2024 - 02/2003
72Insulin Resistance
03/2024 - 09/2003
72COVID-19
02/2024 - 01/2020
70Glioma (Gliomas)
01/2024 - 12/2004
68Atherosclerosis
06/2024 - 02/2006
63Myocardial Infarction
04/2024 - 03/2005
60Hypertension (High Blood Pressure)
04/2024 - 06/2003
57Ischemia
04/2024 - 07/2005
53Leukemia
03/2024 - 09/2007
52Reperfusion Injury
02/2024 - 06/2007
51Prostatic Neoplasms (Prostate Cancer)
01/2024 - 08/2003
48Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
04/2024 - 01/2005
47Necrosis
04/2024 - 07/2005
47Thrombosis (Thrombus)
04/2024 - 08/2007
42Non-alcoholic Fatty Liver Disease
04/2024 - 08/2006
42Rheumatoid Arthritis
02/2024 - 02/2006
42Cognitive Dysfunction
01/2024 - 02/2010
40Adenocarcinoma of Lung
02/2024 - 11/2015
40Schizophrenia (Dementia Praecox)
01/2024 - 08/2005
39Aortic Dissection
04/2024 - 07/2011
39Liver Cirrhosis (Hepatic Cirrhosis)
04/2024 - 01/2009
39Osteoporosis
02/2024 - 08/2009
39Brain Ischemia (Cerebral Ischemia)
11/2023 - 10/2004
38Heart Failure
04/2024 - 08/2010
38Pancreatic Neoplasms (Pancreatic Cancer)
11/2023 - 03/2009
36Parkinson Disease (Parkinson's Disease)
03/2024 - 06/2007
36Glioblastoma (Glioblastoma Multiforme)
03/2024 - 12/2003
36Pneumonia (Pneumonitis)
02/2024 - 09/2008

Drug/Important Bio-Agent (IBA)

454Proteins (Proteins, Gene)FDA Link
12/2024 - 01/2003
350Biomarkers (Surrogate Marker)IBA
04/2024 - 11/2007
182MicroRNAs (MicroRNA)IBA
03/2024 - 05/2012
157CytokinesIBA
04/2024 - 11/2002
145Messenger RNA (mRNA)IBA
04/2024 - 03/2002
141Glucose (Dextrose)FDA LinkGeneric
04/2024 - 09/2003
130RNA (Ribonucleic Acid)IBA
06/2024 - 12/2004
116Long Noncoding RNAIBA
02/2024 - 01/2014
85EnzymesIBA
05/2024 - 10/2003
84Therapeutic UsesIBA
04/2024 - 06/2004
78DNA (Deoxyribonucleic Acid)IBA
01/2024 - 08/2002
76LipidsIBA
04/2024 - 09/2007
69Phosphotransferases (Kinase)IBA
03/2024 - 02/2003
63Peptides (Polypeptides)IBA
06/2024 - 06/2004
63Reactive Oxygen Species (Oxygen Radicals)IBA
04/2024 - 06/2007
62Transcription Factors (Transcription Factor)IBA
03/2024 - 12/2003
62VaccinesIBA
03/2024 - 12/2004
57Cisplatin (Platino)FDA LinkGeneric
03/2024 - 01/2005
57Insulin (Novolin)FDA Link
02/2024 - 09/2003
56Small Interfering RNA (siRNA)IBA
04/2024 - 01/2008
53AntigensIBA
09/2023 - 12/2003
51Indicators and Reagents (Reagents)IBA
03/2024 - 09/2006
50Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2024 - 12/2003
49Circular RNAIBA
09/2023 - 04/2017
49Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2023 - 09/2003
47Anti-Bacterial Agents (Antibiotics)IBA
05/2024 - 07/2009
47Inosine Triphosphate (ITP)IBA
04/2024 - 01/2005
45Interleukin-6 (Interleukin 6)IBA
03/2024 - 02/2005
44Blood Glucose (Blood Sugar)IBA
06/2024 - 07/2010
44AntioxidantsIBA
04/2024 - 01/2007
44LigandsIBA
01/2024 - 12/2004
40Doxorubicin (Adriamycin)FDA LinkGeneric
03/2024 - 01/2009
39CholesterolIBA
03/2024 - 06/2003
39AcidsIBA
11/2023 - 01/2007
36Immune Checkpoint InhibitorsIBA
05/2024 - 01/2020
36CateninsIBA
04/2024 - 07/2013
36Oxygen (Dioxygen)IBA
04/2024 - 06/2006
36InterferonsIBA
04/2024 - 06/2011
36AlbuminsIBA
02/2024 - 01/2012
35LipopolysaccharidesIBA
04/2024 - 10/2006

Therapy/Procedure

644Therapeutics
06/2024 - 07/2003
178Drug Therapy (Chemotherapy)
05/2024 - 12/2005
101Immunotherapy
05/2024 - 12/2007
75Transplantation
04/2024 - 02/2002
72Chinese Traditional Medicine (Traditional Chinese Medicine)
04/2024 - 07/2009
65Radiotherapy
12/2023 - 12/2005
55Stents
04/2024 - 12/2007
42Aftercare (After-Treatment)
04/2024 - 09/2008
37Thrombectomy
02/2024 - 10/2019